Alcohol is more efficient than sugar

Centuries ago, when bulk transportation was expensive and raw foods were at risk of loss to spoilage or pests, distant farmers might prefer to convert sugar-bearing grain and fruit into ethanol, distill it to concentrate it, and transport that concentrate to distant markets. (This fact was a primary cause of the Whiskey Rebellion in response to the imposition of a tax on distilled alcohol.)

I was surprised at how much more efficient ethanol is as a source of energy, even though energy is lost through fermentation! The chemical equation for fermentation of sugar (glucose chosen here) is:

C₆H₁₂O₆ (glucose) → 2C₂H₅OH (ethanol) + 2CO₂ (carbon dioxide) + Energy

Considered by weight: For every kilo of glucose fermented, we get half a kilo of ethanol and 300 calories of heat (which is typically wasted). But ethanol is more energy dense than sugar: Humans extract 3700 calories per kilo of glucose but 7000 calories per kilo of ethanol! I.e., the metabolic energy available in a kilo of sugar is mostly preserved when converted to alcohol, but its weight is cut in half.

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